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Circulating Reactive Oxidant Causes Apoptosis of Retinal Pigment Epithelium and Cone Photoreceptors in the Mouse Central Retina

Reactive oxidants damage the retinal pigment epithelium (RPE), which is required for viability of overlying photoreceptors. Smoking which leads to chronic accumulation of reactive oxidants in the circulation is linked to age-related macular degeneration (AMD) where RPE death is seen along with photo...

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Detalhes bibliográficos
Main Authors: Wang, Wei, Noel, Jennifer, Kaplan, Henry J., Dean, Douglas C.
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661493/
https://ncbi.nlm.nih.gov/pubmed/23861623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/OED.S7797
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