Structural basis of rifampin inactivation by rifampin phosphotransferase

Rifampin (RIF) is a first-line drug used for the treatment of tuberculosis and other bacterial infections. Various RIF resistance mechanisms have been reported, and recently an RIF-inactivation enzyme, RIF phosphotransferase (RPH), was reported to phosphorylate RIF at its C21 hydroxyl at the cost of...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Qi, Xiaofeng, Lin, Wei, Ma, Miaolian, Wang, Chengyuan, He, Yang, He, Nisha, Gao, Jing, Zhou, Hu, Xiao, Youli, Wang, Yong, Zhang, Peng
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833264/
https://ncbi.nlm.nih.gov/pubmed/27001859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523614113
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi