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A heme-binding domain controls regulation of ATP-dependent potassium channels

Heme iron has many and varied roles in biology. Most commonly it binds as a prosthetic group to proteins, and it has been widely supposed and amply demonstrated that subtle variations in the protein structure around the heme, including the heme ligands, are used to control the reactivity of the meta...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Burton, Mark J., Kapetanaki, Sofia M., Chernova, Tatyana, Jamieson, Andrew G., Dorlet, Pierre, Santolini, Jérôme, Moody, Peter C. E., Mitcheson, John S., Davies, Noel W., Schmid, Ralf, Raven, Emma L., Storey, Nina M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833257/
https://ncbi.nlm.nih.gov/pubmed/27006498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600211113
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