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Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase–thioesterase enzyme pair

Halogenated pyrroles (halopyrroles) are common chemical moieties found in bioactive bacterial natural products. The halopyrrole moieties of mono- and dihalopyrrole-containing compounds arise from a conserved mechanism in which a proline-derived pyrrolyl group bound to a carrier protein is first halo...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: El Gamal, Abrahim, Agarwal, Vinayak, Diethelm, Stefan, Rahman, Imran, Schorn, Michelle A., Sneed, Jennifer M., Louie, Gordon V., Whalen, Kristen E., Mincer, Tracy J., Noel, Joseph P., Paul, Valerie J., Moore, Bradley S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833250/
https://ncbi.nlm.nih.gov/pubmed/27001835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519695113
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