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Is rate–pressure product of any use in the isolated rat heart? Assessing cardiac ‘effort’ and oxygen consumption in the Langendorff‐perfused heart

NEW FINDINGS: What is the central question of this study? Rate–pressure product (RPP) is commonly used as an index of cardiac ‘effort’. In canine and human hearts (which have a positive force–frequency relationship), RPP is linearly correlated with oxygen consumption and has therefore been widely ad...

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Pubblicato in:Exp Physiol
Autori principali: Aksentijević, Dunja, Lewis, Hannah R., Shattock, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833194/
https://ncbi.nlm.nih.gov/pubmed/26585840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/EP085380
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