Mycobacterial receptor, Clec4d (CLECSF8, MCL), is coregulated with Mincle and upregulated on mouse myeloid cells following microbial challenge

The C‐type lectin receptor (CTLR), Clec4d (MCL, CLECSF8), is a member of the Dectin‐2 cluster of CTLRs, which also includes the related receptors Mincle and Dectin‐2. Like Mincle, Clec4d recognizes mycobacterial cord factor, trehalose dimycolate, and we recently demonstrated its key role in anti‐myc...

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Publicado en:Eur J Immunol
Autores principales: Kerscher, Bernhard, Wilson, Gillian J., Reid, Delyth M., Mori, Daiki, Taylor, Julie A., Besra, Gurdyal S., Yamasaki, Sho, Willment, Janet A., Brown, Gordon D.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2015
Materias:
Immunity to Infection
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833188/
https://ncbi.nlm.nih.gov/pubmed/26558717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545858
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