The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase

CLECSF8 is a poorly characterized member of the “Dectin-2 cluster” of C-type lectin receptors and was originally thought to be expressed exclusively by macrophages. We show here that CLECSF8 is primarily expressed by peripheral blood neutrophils and monocytes and weakly by several subsets of periphe...

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Główni autorzy: Graham, Lisa M., Gupta, Vandana, Schafer, Georgia, Reid, Delyth M., Kimberg, Matti, Dennehy, Kevin M., Hornsell, William G., Guler, Reto, Campanero-Rhodes, Maria A., Palma, Angelina S., Feizi, Ten, Kim, Stella K., Sobieszczuk, Peter, Willment, Janet A., Brown, Gordon D.
Format: Artigo
Język:Inglês
Wydane: American Society for Biochemistry and Molecular Biology 2012
Hasła przedmiotowe:
Immunology
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406680/
https://ncbi.nlm.nih.gov/pubmed/22689578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.384164
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