Mouse superkiller‐2‐like helicase DDX60 is dispensable for type I IFN induction and immunity to multiple viruses

IFN‐α/β allow cells to fight virus infection by inducing the expression of many genes that encode effectors of antiviral defense. One of these, the Ski2‐like DExH‐box helicase DDX60, was recently implicated in resistance of human cells to hepatitis C virus, as well as in induction of IFN‐α/β by reti...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Immunol
Hauptverfasser: Goubau, Delphine, van der Veen, Annemarthe G., Chakravarty, Probir, Lin, Rongtuan, Rogers, Neil, Rehwinkel, Jan, Deddouche, Safia, Rosewell, Ian, Hiscott, John, Reis e Sousa, Caetano
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
Schlagworte:
Innate Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833184/
https://ncbi.nlm.nih.gov/pubmed/26457795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545794
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