APOE4 carriers and non-carriers with the clinical diagnosis of Alzheimer’s dementia and minimal amyloid plaques

IMPORTANCE: Amyloid-β (Aβ) plaques are a cardinal neuropathological feature of Alzheimer’s disease (AD), yet over a third of apolipoprotein E ε4 (APOE4) non-carriers with the clinical diagnosis of mild-to-moderate Alzheimer’s dementia may not meet positron emission tomography (PET) criteria for sign...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Monsell, Sarah E., Kukull, Walter A., Roher, Alex E., Maarouf, Chera L., Serrano, Geidy, Beach, Thomas G., Caselli, Richard J., Montine, Thomas J., Reiman, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833059/
https://ncbi.nlm.nih.gov/pubmed/26302353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2015.1721
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