Cadmium Induces Histone H3 Lysine Methylation by Inhibiting Histone Demethylase Activity

Cadmium is an established human lung carcinogen with weak mutagenicity. However, the mechanisms underlying cadmium-induced carcinogenesis remain obscure. It has been suggested that epigenetic mechanisms may play a role in cadmium-induced carcinogenesis. In this study, we investigated the effects of...

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Udgivet i:Toxicol Sci
Main Authors: Xiao, Chunlian, Liu, Yin, Xie, Chengfeng, Tu, Wei, Xia, Yujie, Costa, Max, Zhou, Xue
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Cadmium and Histone Methylation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833035/
https://ncbi.nlm.nih.gov/pubmed/25673502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv019
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