Histone Deacetylase Inhibitors Stimulate Histone H3 Lysine 4 Methylation in Part Via Transcriptional Repression of Histone H3 Lysine 4 Demethylases

This study investigates the mechanism by which histone deacetylase (HDAC) inhibitors up-regulate histone H3 lysine 4 (H3K4) methylation. Exposure of LNCaP prostate cancer cells and the prostate tissue of transgenic adenocarcinoma of the mouse prostate mice to the pan- and class I HDAC inhibitors (S)...

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Hlavní autoři: Huang, Po-Hsien, Chen, Chun-Han, Chou, Chih-Chien, Sargeant, Aaron M., Kulp, Samuel K., Teng, Che-Ming, Byrd, John C., Chen, Ching-Shih
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014276/
https://ncbi.nlm.nih.gov/pubmed/20959362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.067702
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