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Evolutionary-guided de novo structure prediction of self-associated transmembrane helical proteins with near-atomic accuracy
How specific protein associations regulate the function of membrane receptors remains poorly understood. Conformational flexibility currently hinders the structure determination of several classes of membrane receptors and associated oligomers. Here we develop EFDOCK-TM, a general method to predict...
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| 出版年: | Nat Commun |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833009/ https://ncbi.nlm.nih.gov/pubmed/25995083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8196 |
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