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Evolutionary-guided de novo structure prediction of self-associated transmembrane helical proteins with near-atomic accuracy
How specific protein associations regulate the function of membrane receptors remains poorly understood. Conformational flexibility currently hinders the structure determination of several classes of membrane receptors and associated oligomers. Here we develop EFDOCK-TM, a general method to predict...
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| Publicado no: | Nat Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833009/ https://ncbi.nlm.nih.gov/pubmed/25995083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8196 |
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