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Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories

Neurodegeneration with brain iron accumulation (NBIA) is a group of disorders characterized by dystonia, parkinsonism and spasticity. Iron accumulates in the basal ganglia and may be accompanied by Lewy bodies, axonal swellings and hyperphosphorylated tau depending on NBIA subtype. Mutations in 10 g...

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Detalhes bibliográficos
Publicado no:Neuropathol Appl Neurobiol
Main Authors: Arber, C. E., Li, A., Houlden, H., Wray, S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832581/
https://ncbi.nlm.nih.gov/pubmed/25870938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12242
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