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Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories

Neurodegeneration with brain iron accumulation (NBIA) is a group of disorders characterized by dystonia, parkinsonism and spasticity. Iron accumulates in the basal ganglia and may be accompanied by Lewy bodies, axonal swellings and hyperphosphorylated tau depending on NBIA subtype. Mutations in 10 g...

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Pubblicato in:Neuropathol Appl Neurobiol
Autori principali: Arber, C. E., Li, A., Houlden, H., Wray, S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832581/
https://ncbi.nlm.nih.gov/pubmed/25870938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12242
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