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OncoNEM: inferring tumor evolution from single-cell sequencing data

Single-cell sequencing promises a high-resolution view of genetic heterogeneity and clonal evolution in cancer. However, methods to infer tumor evolution from single-cell sequencing data lag behind methods developed for bulk-sequencing data. Here, we present OncoNEM, a probabilistic method for infer...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Ross, Edith M., Markowetz, Florian
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832472/
https://ncbi.nlm.nih.gov/pubmed/27083415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0929-9
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