Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+ and CD45RO+ CD4+CD25+CD127(low) Treg Cells in Patients With Chronic Rheumatoid Arthritis

OBJECTIVE: Conflicting evidence exists regarding the suppressive capacity of Treg cells in the peripheral blood (PB) of patients with rheumatoid arthritis (RA). The aim of this study was to determine whether Treg cells are intrinsically defective in RA. METHODS: Using a range of assays on PB samples...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Walter, Gina J., Fleskens, Veerle, Frederiksen, Klaus S., Rajasekhar, Megha, Menon, Bina, Gerwien, Jens G., Evans, Hayley G., Taams, Leonie S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Rheumatoid Arthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832388/
https://ncbi.nlm.nih.gov/pubmed/26314565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39408
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