VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8

Vascular endothelial growth factor A (VEGF‐A) regulates many aspects of vascular function. VEGF‐A binding to vascular endothelial growth factor receptor 2 (VEGFR2) stimulates endothelial signal transduction and regulates multiple cellular responses. Activated VEGFR2 undergoes ubiquitination but the...

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Pubblicato in:Traffic
Autori principali: Smith, Gina A., Fearnley, Gareth W., Abdul‐Zani, Izma, Wheatcroft, Stephen B., Tomlinson, Darren C., Harrison, Michael A., Ponnambalam, Sreenivasan
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons A/S 2015
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832373/
https://ncbi.nlm.nih.gov/pubmed/26459808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12341
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