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Incorporating Functional Genomic Information in Genetic Association Studies Using an Empirical Bayes Approach

There is a large amount of functional genetic data available, which can be used to inform fine‐mapping association studies (in diseases with well‐characterised disease pathways). Single nucleotide polymorphism (SNP) prioritization via Bayes factors is attractive because prior information can inform...

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Dettagli Bibliografici
Pubblicato in:Genet Epidemiol
Autori principali: Spencer, Amy V., Cox, Angela, Lin, Wei‐Yu, Easton, Douglas F., Michailidou, Kyriaki, Walters, Kevin
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832271/
https://ncbi.nlm.nih.gov/pubmed/26833494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21956
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