Measuring Extracellular pH in a Lung Fibrosis Model with acidoCEST MRI

PURPOSE: A feed-forward loop involving lactic acid production may potentially occur during the formation of idiopathic pulmonary fibrosis. To provide evidence for this feed-forward loop, we used acidoCEST MRI to measure the extracellular pH (pHe), while also measuring percent uptake of the contrast...

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Gepubliceerd in:Mol Imaging Biol
Hoofdauteurs: Jones, Kyle M., Randtke, Edward A., Howison, Christine M., Cárdenas-Rodríguez, Julio, Sime, Patricia J., Kottmann, R. Matthew, Pagel, Mark D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832114/
https://ncbi.nlm.nih.gov/pubmed/25187227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-014-0784-6
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