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Respiration gating and Bloch fitting improve pH measurements with acidoCEST MRI in an ovarian orthotopic tumor model

We have developed a MRI method that can measure extracellular pH in tumor tissues, known as acidoCEST MRI. This method relies on the detection of Chemical Exchange Saturation Transfer (CEST) of iopamidol, an FDA-approved CT contrast agent that has two CEST signals. A log(10) ratio of the two CEST si...

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Detalhes bibliográficos
Publicado no:Proc SPIE Int Soc Opt Eng
Main Authors: Jones, Kyle M, Randtke, Edward A, Howison, Christine M, Pagel, Mark D
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871271/
https://ncbi.nlm.nih.gov/pubmed/27212783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/12.2216418
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