Transcriptomics in type 2 diabetes: Bridging the gap between genotype and phenotype

Type 2 diabetes (T2D) is a common, multifactorial disease that is influenced by genetic and environmental factors and their interactions. However, common variants identified by genome wide association studies (GWAS) explain only about 10% of the total trait variance for T2D and less than 5% of the v...

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Dettagli Bibliografici
Pubblicato in:Genom Data
Autori principali: Jenkinson, Christopher P., Göring, Harald H.H., Arya, Rector, Blangero, John, Duggirala, Ravindranath, DeFronzo, Ralph A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
Soggetti:
Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832048/
https://ncbi.nlm.nih.gov/pubmed/27114903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gdata.2015.12.001
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