Unique epigenetic influence of H2AX phosphorylation and H3K56 acetylation on normal stem cell radioresponses

Normal tissue injury resulting from cancer radiotherapy is often associated with diminished regenerative capacity. We examined the relative radiosensitivity of normal stem cell populations compared with non–stem cells within several radiosensitive tissue niches and culture models. We found that thes...

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Publicat a:Mol Biol Cell
Autors principals: Jacobs, Keith M., Misri, Sandeep, Meyer, Barbara, Raj, Suyash, Zobel, Cheri L., Sleckman, Barry P., Hallahan, Dennis E., Sharma, Girdhar G.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831886/
https://ncbi.nlm.nih.gov/pubmed/26941327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-01-0017
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