Mechanical confinement triggers glioma linear migration dependent on formin FHOD3

Glioblastomas are extremely aggressive brain tumors with highly invasive properties. Brain linear tracks such as blood vessel walls constitute their main invasive routes. Here we analyze rat C6 and patient-derived glioma cell motility in vitro using micropatterned linear tracks to mimic blood vessel...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Monzo, Pascale, Chong, Yuk Kien, Guetta-Terrier, Charlotte, Krishnasamy, Anitha, Sathe, Sharvari R., Yim, Evelyn K. F., Ng, Wai Hoe, Ang, Beng Ti, Tang, Carol, Ladoux, Benoit, Gauthier, Nils C., Sheetz, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831879/
https://ncbi.nlm.nih.gov/pubmed/26912794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-08-0565
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