Mechanical confinement triggers glioma linear migration dependent on formin FHOD3

Glioblastomas are extremely aggressive brain tumors with highly invasive properties. Brain linear tracks such as blood vessel walls constitute their main invasive routes. Here we analyze rat C6 and patient-derived glioma cell motility in vitro using micropatterned linear tracks to mimic blood vessel...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Monzo, Pascale, Chong, Yuk Kien, Guetta-Terrier, Charlotte, Krishnasamy, Anitha, Sathe, Sharvari R., Yim, Evelyn K. F., Ng, Wai Hoe, Ang, Beng Ti, Tang, Carol, Ladoux, Benoit, Gauthier, Nils C., Sheetz, Michael P.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831879/
https://ncbi.nlm.nih.gov/pubmed/26912794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-08-0565
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