trappc11 is required for protein glycosylation in zebrafish and humans

Activation of the unfolded protein response (UPR) can be either adaptive or pathological. We term the pathological UPR that causes fatty liver disease a “stressed UPR.” Here we investigate the mechanism of stressed UPR activation in zebrafish bearing a mutation in the trappc11 gene, which encodes a...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: DeRossi, Charles, Vacaru, Ana, Rafiq, Ruhina, Cinaroglu, Ayca, Imrie, Dru, Nayar, Shikha, Baryshnikova, Anastasia, Milev, Miroslav P., Stanga, Daniela, Kadakia, Dhara, Gao, Ningguo, Chu, Jaime, Freeze, Hudson H., Lehrman, Mark A., Sacher, Michael, Sadler, Kirsten C.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831877/
https://ncbi.nlm.nih.gov/pubmed/26912795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-08-0557
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