Structural comparison of the Caenorhabditis elegans and human Ndc80 complexes bound to microtubules reveals distinct binding behavior

During cell division, kinetochores must remain tethered to the plus ends of dynamic microtubule polymers. However, the molecular basis for robust kinetochore–microtubule interactions remains poorly understood. The conserved four-subunit Ndc80 complex plays an essential and direct role in generating...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Wilson-Kubalek, Elizabeth M., Cheeseman, Iain M., Milligan, Ronald A.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2016
Subjects:
Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831874/
https://ncbi.nlm.nih.gov/pubmed/26941333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-12-0858
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