Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR

Hyperammonemia is frequently seen in tumor microenvironments as well as in liver diseases where it can lead to severe brain damage or death. Ammonia induces autophagy, a mechanism that tumor cells may use to protect themselves from external stresses. However, how cells sense ammonia has been unclear...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Li, Zhiyuan, Ji, Xinmiao, Wang, Wenchao, Liu, Juanjuan, Liang, Xiaofei, Wu, Hong, Liu, Jing, Eggert, Ulrike S., Liu, Qingsong, Zhang, Xin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831814/
https://ncbi.nlm.nih.gov/pubmed/27077655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153526
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