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The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer

Squamous cell carcinoma of the head and neck (SCCHN) is an aggressive disease with poor survival and is the sixth most common cancer worldwide. Gastroesophageal reflux is a common event in SCCHN patients. GPR4 is a proton-sensing G-protein coupled receptor, which can be activated by acidosis. The ob...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Jing, Zhibin, Xu, Hongbo, Chen, Xiaohong, Zhong, Qi, Huang, Junwei, Zhang, Yang, Guo, Wei, Yang, Zheng, Ding, Shuo, Chen, Ping, Huang, Zhigang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831743/
https://ncbi.nlm.nih.gov/pubmed/27078157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152789
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