The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer

Squamous cell carcinoma of the head and neck (SCCHN) is an aggressive disease with poor survival and is the sixth most common cancer worldwide. Gastroesophageal reflux is a common event in SCCHN patients. GPR4 is a proton-sensing G-protein coupled receptor, which can be activated by acidosis. The ob...

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Veröffentlicht in:PLoS One
Hauptverfasser: Jing, Zhibin, Xu, Hongbo, Chen, Xiaohong, Zhong, Qi, Huang, Junwei, Zhang, Yang, Guo, Wei, Yang, Zheng, Ding, Shuo, Chen, Ping, Huang, Zhigang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831743/
https://ncbi.nlm.nih.gov/pubmed/27078157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152789
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