Cloning and Characterization of a Human Genomic Sequence that Alleviates Repeat-Induced Gene Silencing

Plasmids bearing a mammalian replication initiation region (IR) and a nuclear matrix attachment region (MAR) are spontaneously amplified in transfected mammalian cells, and such amplification generates chromosomal homogeneously staining regions (HSRs) or extrachromosomal double minutes (DMs). This m...

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Veröffentlicht in:PLoS One
Hauptverfasser: Fukuma, Miki, Ganmyo, Yuto, Miura, Osamu, Ohyama, Takashi, Shimizu, Noriaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831671/
https://ncbi.nlm.nih.gov/pubmed/27078685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153338
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