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Preclinical exploration of combining plasmacytoid and myeloid dendritic cell vaccination with BRAF inhibition

BACKGROUND: Melanoma is the most lethal type of skin cancer and its incidence is progressively increasing. The introductions of immunotherapy and targeted therapies have tremendously improved the treatment of melanoma. Selective inhibition of BRAF by vemurafenib results in objective clinical respons...

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Bibliografische gegevens
Gepubliceerd in:J Transl Med
Hoofdauteurs: Tel, Jurjen, Koornstra, Rutger, de Haas, Nienke, van Deutekom, Vincent, Westdorp, Harm, Boudewijns, Steve, van Erp, Nielka, Di Blasio, Stefania, Gerritsen, Winald, Figdor, Carl G., de Vries, I. Jolanda M., Hato, Stanleyson V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831164/
https://ncbi.nlm.nih.gov/pubmed/27075584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0844-6
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