Preclinical exploration of combining plasmacytoid and myeloid dendritic cell vaccination with BRAF inhibition

BACKGROUND: Melanoma is the most lethal type of skin cancer and its incidence is progressively increasing. The introductions of immunotherapy and targeted therapies have tremendously improved the treatment of melanoma. Selective inhibition of BRAF by vemurafenib results in objective clinical respons...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Tel, Jurjen, Koornstra, Rutger, de Haas, Nienke, van Deutekom, Vincent, Westdorp, Harm, Boudewijns, Steve, van Erp, Nielka, Di Blasio, Stefania, Gerritsen, Winald, Figdor, Carl G., de Vries, I. Jolanda M., Hato, Stanleyson V.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831164/
https://ncbi.nlm.nih.gov/pubmed/27075584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0844-6
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