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Necrotic cells influence migration and invasion of glioblastoma via NF-κB/AP-1-mediated IL-8 regulation

Glioblastoma multiforme (GBM) is the most common primary intracranial tumor in adults and has poor prognosis. Diffuse infiltration into normal brain parenchyma, rapid growth, and the presence of necrosis are remarkable hallmarks of GBM. However, the effect of necrotic cells on GBM growth and metasta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ahn, So-Hee, Park, Hyunju, Ahn, Young-Ho, Kim, Sewha, Cho, Min-Sun, Kang, Jihee Lee, Choi, Youn-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830983/
https://ncbi.nlm.nih.gov/pubmed/27076368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24552
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