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Necrotic cells influence migration and invasion of glioblastoma via NF-κB/AP-1-mediated IL-8 regulation

Glioblastoma multiforme (GBM) is the most common primary intracranial tumor in adults and has poor prognosis. Diffuse infiltration into normal brain parenchyma, rapid growth, and the presence of necrosis are remarkable hallmarks of GBM. However, the effect of necrotic cells on GBM growth and metasta...

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Publicado en:Sci Rep
Autores principales: Ahn, So-Hee, Park, Hyunju, Ahn, Young-Ho, Kim, Sewha, Cho, Min-Sun, Kang, Jihee Lee, Choi, Youn-Hee
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830983/
https://ncbi.nlm.nih.gov/pubmed/27076368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24552
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