A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11

Meiosis is the biological process that, after a cycle of DNA replication, halves the cellular chromosome complement, leading to the formation of haploid gametes. Haploidization is achieved via two successive rounds of chromosome segregation, meiosis I and II. In mammals, during prophase of meiosis I...

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Udgivet i:Chromosoma
Main Authors: Faieta, Monica, Di Cecca, Stefano, de Rooij, Dirk G., Luchetti, Andrea, Murdocca, Michela, Di Giacomo, Monica, Di Siena, Sara, Pellegrini, Manuela, Rossi, Pellegrino, Barchi, Marco
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830894/
https://ncbi.nlm.nih.gov/pubmed/26440409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-015-0544-7
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