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Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease

Several lines of evidence point to a significant role of neuroinflammation in Parkinson's disease (PD) and other neurodegenerative disorders. In the present study we examined the protective effect of celecoxib, a selective inhibitor of the inducible form of cyclooxygenase (COX-2), on dopamine (...

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Detalhes bibliográficos
Main Authors: Sánchez-Pernaute, Rosario, Ferree, Andrew, Cooper, Oliver, Yu, Meixiang, Brownell, Anna-Liisa, Isacson, Ole
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC483059/
https://ncbi.nlm.nih.gov/pubmed/15285796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-1-6
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