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Increased cell membrane capacitance is the dominant mechanism of stretch-dependent conduction slowing in the rabbit heart: a computational study

Volume loading of the cardiac ventricles is known to slow electrical conduction in the rabbit heart, but the mechanisms remain unclear. Previous experimental and modeling studies have investigated some of these mechanisms, including stretch-activated membrane currents, reduced gap junctional conduct...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Mol Bioeng
Hauptverfasser: de Oliveira, Bernardo L., Pfeiffer, Emily R., Sundnes, Joakim, Wall, Samuel T., McCulloch, Andrew D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830494/
https://ncbi.nlm.nih.gov/pubmed/27087858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-015-0384-9
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