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pH-Responsive Artemisinin Dimer in Lipid Nanoparticles Are Effective Against Human Breast Cancer in a Xenograft Model

Artemisinin (ART), a well-known antimalaria drug, also exhibits anticancer activities. We previously reported a group of novel dimeric artemisinin piperazine conjugates (ADPs) possessing pH-dependent aqueous solubility and a proof-of-concept lipid nanoparticle formulation based on natural egg phosph...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: ZHANG, YITONG J., ZHAN, XI, WANG, LIGUO, HO, RODNEY J.Y., SASAKI, TOMIKAZU
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830345/
https://ncbi.nlm.nih.gov/pubmed/25753991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24407
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