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Enhanced anti-HIV efficacy of Indinavir after inclusion in CD4 targeted lipid nanoparticles

BACKGROUND: Combination drug therapy has reduced plasma HIV to undetectable levels; however, drug sensitive virus persists in patients’ lymphoid tissue. We have reported significant lymphoid tissue drug localization with Indinavir-associated lipid nanoparticles (LNPs). Our current objective is to ev...

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Detalhes bibliográficos
Main Authors: Endsley, Aaron N., Ho, Rodney J.Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551348/
https://ncbi.nlm.nih.gov/pubmed/22743598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3182653c1f
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