Comparative Analysis of Novel Noninvasive Renal Biomarkers and Metabonomic Changes in a Rat Model of Gentamicin Nephrotoxicity

Although early detection of toxicant induced kidney injury during drug development and chemical safety testing is still limited by the lack of sensitive and reliable biomarkers of nephrotoxicity, omics technologies have brought enormous opportunities for improved detection of toxicity and biomarker...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Sieber, Max, Hoffmann, Dana, Adler, Melanie, Vaidya, Vishal S., Clement, Matthew, Bonventre, Joseph V., Zidek, Nadine, Rached, Eva, Amberg, Alexander, Callanan, John J., Dekant, Wolfgang, Mally, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Safety Assessment
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830225/
https://ncbi.nlm.nih.gov/pubmed/19349640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp070
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