Comparative Analysis of Novel Noninvasive Renal Biomarkers and Metabonomic Changes in a Rat Model of Gentamicin Nephrotoxicity

Although early detection of toxicant induced kidney injury during drug development and chemical safety testing is still limited by the lack of sensitive and reliable biomarkers of nephrotoxicity, omics technologies have brought enormous opportunities for improved detection of toxicity and biomarker...

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Dades bibliogràfiques
Publicat a:Toxicol Sci
Autors principals: Sieber, Max, Hoffmann, Dana, Adler, Melanie, Vaidya, Vishal S., Clement, Matthew, Bonventre, Joseph V., Zidek, Nadine, Rached, Eva, Amberg, Alexander, Callanan, John J., Dekant, Wolfgang, Mally, Angela
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
Matèries:
Safety Assessment
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830225/
https://ncbi.nlm.nih.gov/pubmed/19349640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp070
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