Safety of targeting tumor endothelial cell antigens

The mechanisms underlying discrimination between “self” and “non-self”, a central immunological principle, require careful consideration in immune oncology therapeutics where eliciting anti-cancer immunity must be weighed against the risk of autoimmunity due to the self origin of tumors. Whole cell...

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Bibliographic Details
Published in:J Transl Med
Main Authors: Wagner, Samuel C., Riordan, Neil H., Ichim, Thomas E., Szymanski, Julia, Ma, Hong, Perez, Jesus A., Lopez, Javier, Plata-Munoz, Juan J., Silva, Francisco, Patel, Amit N., Kesari, Santosh
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830034/
https://ncbi.nlm.nih.gov/pubmed/27071457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0842-8
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