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Cancer anti-angiogenesis vaccines: Is the tumor vasculature antigenically unique?
Angiogenesis is essential for the growth and metastasis of solid tumors. The tumor endothelium exists in a state of chronic activation and proliferation, fueled by the tumor milieu where angiogenic mediators are aberrantly over-expressed. Uncontrolled tumor growth, immune evasion, and therapeutic re...
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| Publicado no: | J Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4625691/ https://ncbi.nlm.nih.gov/pubmed/26510973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0688-5 |
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