Induction of tumor inhibitory anti-angiogenic response through immunization with interferon Gamma primed placental endothelial cells: ValloVax™

BACKGROUND: While the concept of angiogenesis blockade as a therapeutic intervention for cancer has been repeatedly demonstrated, the full promise of this approach has yet to be realized. Specifically, drugs such as VEGF-blocking antibodies or kinase inhibitors suffer from the drawbacks of resistanc...

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Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: Ichim, Thomas E, Li, Shuang, Ma, Hong, Yurova, Yuliya V, Szymanski, Julia S, Patel, Amit N, Kesari, Santosh, Min, Wei-Ping, Wagner, Samuel C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363400/
https://ncbi.nlm.nih.gov/pubmed/25889119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0441-0
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