Critical Length of PEG Grafts on lPEI/DNA Nanoparticles for Efficient in Vivo Delivery

[Image: see text] Nanoparticle-mediated gene delivery is a promising alternative to viral methods; however, its use in vivo, particularly following systemic injection, has suffered from poor delivery efficiency. Although PEGylation of nanoparticles has been successfully demonstrated as a strategy to...

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Bibliografiske detaljer
Udgivet i:ACS Biomater Sci Eng
Main Authors: Williford, John-Michael, Archang, Maani M., Minn, Il, Ren, Yong, Wo, Mark, Vandermark, John, Fisher, Paul B., Pomper, Martin G., Mao, Hai-Quan
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2016
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829937/
https://ncbi.nlm.nih.gov/pubmed/27088129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.5b00551
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