Continuous Production of Discrete Plasmid DNA-Polycation Nanoparticles Using Flash Nanocomplexation

Despite successful demonstration of linear polyethyleneimine (lPEI) as an effective carrier for a wide range of gene medicine, including DNA plasmids, small interfering RNAs, mRNAs, etc., and continuous improvement of the physical properties and biological performance of the polyelectrolyte complex...

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Vydáno v:Small
Hlavní autoři: Santos, Jose Luis, Ren, Yong, Vandermark, John, Archang, Maani M., Williford, John-Michael, Liu, Heng-wen, Lee, Jason, Wang, Tza-Huei, Mao, Hai-Quan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149445/
https://ncbi.nlm.nih.gov/pubmed/27717227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201601425
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