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Astrocytes contribute to synapse elimination via type 2 inositol 1,4,5-trisphosphate receptor-dependent release of ATP
Selective elimination of unwanted synapses is vital for the precise formation of neuronal circuits during development, but the underlying mechanisms remain unclear. Using inositol 1,4,5-trisphosphate receptor type 2 knockout (Itpr2(−/−)) mice to specifically disturb somatic Ca(2+) signaling in astro...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4829431/ https://ncbi.nlm.nih.gov/pubmed/27067238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15043 |
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