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Inhibition of inositol trisphosphate-induced calcium release by caffeine is prevented by ATP.

We have investigated the effect of various methylxanthines on the basal and InsP3-stimulated unidirectional 45Ca2+ efflux from permeabilized A7r5 cells under different experimental conditions. We report that caffeine and theophylline inhibit the InsP3-induced Ca2+ release, whereas the basal Ca2+ lea...

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Detalles Bibliográficos
Main Authors: Missiaen, L, Parys, J B, De Smedt, H, Himpens, B, Casteels, R
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138126/
https://ncbi.nlm.nih.gov/pubmed/8198556
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