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A General Method for Aminoquinoline-Directed, Copper-Catalyzed sp(2) C–H Bond Amination

An operationally simple and general method for copper-catalyzed, aminoquinoline-assisted amination of β-C(sp(2))-H bonds of benzoic acid derivatives is reported. The reaction employs Cu(OAc)(2) or (CuOH)(2)CO(3) catalysts, an amine coupling partner, and oxygen from air as a terminal oxidant. Excepti...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Roane, James, Daugulis, Olafs
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829344/
https://ncbi.nlm.nih.gov/pubmed/26990413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b01117
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