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Telomere biology: Rationale for diagnostics and therapeutics in cancer

The key step of carcinogenesis is the malignant transformation which is fundamentally a telomere biology dysfunction permitting cells to bypass the Hayflick limit and to divide indefinitely and uncontrollably. Thus all partners and structures involved in normal and abnormal telomere maintenance, pro...

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Bibliografski detalji
Izdano u:RNA Biol
Glavni autori: Rousseau, Philippe, Autexier, Chantal
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829327/
https://ncbi.nlm.nih.gov/pubmed/26291128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1081329
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